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中国农学通报

中国农学通报 ›› 2005, Vol. 21 ›› Issue (6): 164-164.

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植物雌激素槲皮素对非洲爪蟾生长和骨骼发育的影响

丛 琳,,秦占芬,蒋湘宁,周景明,杨 蕾,,徐晓白   

  • 出版日期:2005-06-05 发布日期:2005-06-05

The Influence of Quercetin on the Growth and Skeletal development of Xenopus laevis

Cong Lin,, Qin Zhanfen, Jiang Xiangning, Zhou Jingming, Yang Lei,, Xu Xiaobai   

  • Online:2005-06-05 Published:2005-06-05

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摘要： 用两栖动物非洲爪蟾作模型动物，来揭示植物雌激素槲皮素对非洲爪蟾生长和骨骼发育的影响。非洲爪蟾从46/47期开始，分别暴露50μg/L，100μg/L，200μg/L槲皮素，直至变态后1个月。结果表明槲皮素处理一方面促进蝌蚪体重的增加，另一方面导致尾的畸形。200μg/L槲皮素还导致脊柱的畸形，表现为少一块脊椎骨。

Abstract: In this study, we examined effects of phytoestrogen quercetin on the growth and skeletal development using amphibian Xenopus laevis as model animals. X. laevis were exposed to quercetin (50μg/L, 100μg/L, 200μg/L) from stage 46/47 to one month postmetamorphosis. The results showed that quercetin promoted body weigh gain and induced tail malformations. Exposure of 200μg/L quercetin caused vertebral malformations, which exhibited loss of a vertebra compared to the normal.