功能性食品在抗癌症方面的应用

摘要/Abstract

摘要： 所谓功能性食品就是指在满足基本的营养需要的同时还能够发挥额外的生理作用，如预防或延迟慢性疾病的发作等。过去数十年的研究已经发现了大量的可以防止细胞氧化的营养物质。这些水果和蔬菜中的成分能够作为抗氧化剂清除体内的有害的能引起疾病的自由基。功能性食品在抗癌症方面有着广阔的应用前景。

Abstract: It is called of functional foods that should be capable of providing additional physiological benefit, such as preventing or delaying onset of chronic diseases, as well as meeting basic nutritional requirements. Some of the most exciting research in the last decade has been the discovery of a group of nutrients, which have protective effects against cell oxidation. These compounds of fruits and vegetables act as antioxidants in the body by scavenging harmful free radicals, which are implicated in most degenerative diseases. It seems that functional foods will be wildly used against cancer.

陈东海,欧阳虹. 功能性食品在抗癌症方面的应用[J]. 中国农学通报, 2005, 21(3): 98-98.

Chen Donghai, Ouyang Hong. Review of the Application of Functional Food against Cancer[J]. Chinese Agricultural Science Bulletin, 2005, 21(3): 98-98.

参考文献

1 Dillard C J, German J B. Phytochemicals: nutraceuticals and human health[J]. Journal of the Science of Food and Agriculture, 2000, 80: 1744~1756
2 Prior R L, Cao G. Antioxidant phytochemicals in fruits and vegetables: diet and health implications[J]. Horticulture Science, 2000, 35: 588~592
3 Sun C, Wang J W, Fang L, et al. Free radical scavenging and antioxidant activities of EPS2, an exopolysaccharide produced by a marine filamentous fungus Keissleriella sp. YS 4108[J]. Life Sciences, 2004,9(75):1063~1073
4 Kumarasamy S, Selvaraj A, Namasivayam N. Evidence of oxidative stress in the circulation of ovarian cancer patients[J]. Clinica Chimica Acta, 2004, 339(1-2):27~32
5 Suby O, John A R, Gopal S. Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells[J]. European Journal of Pharmacology, 2004, 485 (1-3):97~103
6 Archana S, Sharmistha G, Sukta D. Administration of garlic and tomato can protect from carcinogen induced clastogenicity[J]. Nutrition Research, 2002, 22 (7):859~866
7 Seetharaman B, Chinnamanoor R, Siddavaram N. Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic[J]. Fitoterapia, 2001,5(72): 524~531
8 Collaborative, Group on Hormonal Factors in Breast Cancer, Breast cancer and abortion: collaborative reanalysis of data from 53 epidemiological studies, including 83 000 women with breast cancer from 16 countries[J]. The Lancet, 2004, 9414(363): 1007~1016
9 Charlotta D, Chen J M, Wang L D. Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts[J]. Cancer Letters, 2002, 185 (1):31~37
10 Trentin G A, Moody J, Torous D K. The influence of dietary flaxseed and other grains, fruits and vegetables on the frequency of spontaneous chromosomal damage in mice[J]. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004, 551 (1-2): 213~222
11 Trentin G A, Moody J, Shima N. Effect of dietary supplementation on the frequency of spontaneous lacZ mutations in the developing colon[J]. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004, 551 (1-2):223~231
12 Nathalie D, Wim V B, Soy D N A. isoflavone phyto-pharmaceuticals in interleukin-6 affections: Multi-purpose nutraceuticals at the crossroad of hormone replacement, anti-cancer and anti-inflammatory therapy[J]. Biochemical Pharmacology, 2004, 68 (6): 1171~1185
13 Zora D, Chen G, Doerge D R. Effect of soy isoflavone supplementation on markers of oxidative stress in men and women[J]. Cancer Letters, 2001, 172 (1):1~6
14 Patrick M, Akiyo H, Kalidas S. Mobilization of phenolic antioxidants from defatted soybean powders by Lentinus edodes during solid-state bioprocessing1 is associated with enhanced production of laccase[J]. Innovative Food Science and Emerging Technologies, 2004,3(5): 385~392
15 Manisha S, Tak S, Wang C Y. The Soy Isoflavone, Genistein, Protects Human Cortical Neuronal Cells from Oxidative Stress[J]. Neurotoxicology, 2004, 25 (5): 885~891
16 Karakaya S, Kavas A. Antimutagenic activities of some foods[J]. Journal of Agricultural Food Chemistry, 1999, 79: 237~242
17 Deighton N, Brennan R, Finn C, et al, Antioxidant properties of domesticated and wild Rubus species [J], Journal of the Science of Food and Agriculture, 2000, 80: 1307~1313
18 Torronen R. Flavonols and ellagic acid in berries[J]. Recent Advances in Agricultural and Food Chemistry, 2000,1: 31~37
19 Gil M I, Tomas-Barberan F A, Hess- Pierce B, et al. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing[J]. Journal of Agricultural Food Chemistry, 2000, 48: 4581~4589
20 Barqawi Albaha, Gamito Eduard, O'Donnell Colin, Herbal and vitamin supplement use in a prostate cancer screening population[J]. Urology, 2004, 63 (2): 288~292
21 Robichová S, Slamenová D, Chalupa I. DNA lesions and cytogenetic changes induced by N-nitrosomorpholine in HepG2, V79 and VH10 cells: the protective effects of Vitamins A, C and E[J]. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2004, 560 (2):91~99