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中国农学通报 ›› 2005, Vol. 21 ›› Issue (4): 80-80.

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Advances of Researches on the Mechanism of Transgene Silencing in Transgenic Plants

刘悦萍,赵晓萌,宫 飞   

  • 出版日期:2005-04-05 发布日期:2005-04-05

Advances of Researches on the Mechanism of Transgene Silencing in Transgenic Plants

Liu Yueping, Zhao Xiaomeng, Gong Fei   

  • Online:2005-04-05 Published:2005-04-05

摘要: 转基因沉默是导致外源基因不能在转化植株中正常表达的重要原因。在此,从转录水平和转录后水平两个方面,综述了转基因植物中外源基因沉默的机制。DNA甲基化是引起外源基因沉默的主要原因。人们目前用以下几种模型来解释转录后水平基因沉默的机制,如RNA 阈值模型、异常RNA和异位配对模型及双链RNA 模型。对外源基因沉默机制的探讨是顺利开展植物基因工程的迫切要求,也将促进植物功能基因组学研究的进一步深入。

Abstract: Transgene silencing is one of the most important reasons that transgene can not express. This review introduces research progress on the mechanism of plant transgene silencing at transcriptional gene silencing (TGS) and post-transcriptional gene silencing