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中国农学通报 ›› 2006, Vol. 22 ›› Issue (2): 28-28.

所属专题: 生物技术

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CFL2基因研究进展

宋慧娟,苏玉虹   

  • 出版日期:2006-02-05 发布日期:2006-02-05

Advances in the Research of CFL2 Gene

Song Huijuan, Su Yuhong   

  • Online:2006-02-05 Published:2006-02-05

摘要: CFL2(Cofilin 2)基因是肌动蛋白结合蛋白cofilin家族的新成员,主要在哺乳动物的骨骼肌和心肌表达,被认为是肌肉组织肌动蛋白装配的调节器,对正常肌肉功能和肌肉再生起着重要的作用。目前未见对CFL2基因进行全面介绍的文章,因此拟对CFL2基因的表达、结构、蛋白功能及其与肌病相关性方面的研究进展作一综述。

Abstract: CFL2(Cofilin 2)is a new member of the cofilin family of actin-binding proteins, which is expressed predominantly in mammals skeletal muscle and heart. CFL2 is a regulator for actin assembly in muscle and may plays an important role in normal muscle function and muscle regeneration. The overall articles on the CFL2 gene are not been reported currently. This text makes an overview about the expression and the structure of CFL2 gene, protein functions and its role in myopathies.

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