Abstract: Bayberry(Myrica rubra) leaf blight is one of the important diseases occurring on bayberry in hunan province.It was identified that Phomopsis myricina Y.J.Huang et P.K.Chi was the pathogen of bayberry leaf blight.Twenty fungicides were screened at four concentrations in laboratory.The results showed that Thiophanate-methyl.thiram,carbendazim,Junkexing,Tuzet,Manzat,Mancozeb,Asomate,Thiophanate-methyl,Tanbiling and 1:1:100 Bordeaux mixtures were most effective in vitro against the mycelial growth and conidial germination of P. myricina. Xiangyanzhibingling and Hongsha could inhibit effectively against the mycelial growth,but could not inhibit the conidial germination. Fosetyl-aluminium.maneozeb, Dacoden and Lime sulphur could inhibit the conidial germination and could not inhibit the mycelial growth.while the other fungicides were both ineffective against the mycelial growth and conidial germination.