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中国农学通报 ›› 2005, Vol. 21 ›› Issue (1): 8-8.

所属专题: 畜牧兽医

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奶牛MHC及其免疫学研究进展

高树新,,,许尚忠,李金泉,马 云,,王国赋   

  • 出版日期:2005-01-05 发布日期:2005-01-05

MHC of Dairy Cattle and Its Immunological Progress

Gao Shuxin,,,Xu shangzhong,Li Jinquan,Ma Yun,Wang Guofu,   

  • Online:2005-01-05 Published:2005-01-05

摘要: 奶牛MHC又称白细胞抗原,它不仅与移植排斥反应有关,而且广泛参与免疫反应的应答和调节。阐述了MHC的基因结构、MHC的免疫作用、MHC与疾病的关系以及在MAS中如何对实验材料和统计方法进行选择、怎样对待复杂病因疾病与MHC的关系等,最后展望了MHC作为动物抗病力的一种遗传标记的应用前景。

Abstract: Major host-compatibility complex of dairy cattle was also called Bovine Leucocyte Antigen. It is concerned with repulsion response of transplantation and widely involved in adjusting and responsing of immunological response. Recent progress on MHC including its characteristics of chemical structure, function and of gene were summarized in this paper. The distinct immunological function of MHC and related issue concerned with its applicating on MAS of dairy cattle were especially introduced. At last, the future of MHC applied in animal disease-resistance breeding was discussed in this review.