Abstract: The paper aims to determine the toxicity and field efficacy of several common insecticides against Plutella xylostella resistance populations, and then clear the correlation between the resistance level and the control efficacy of insecticides. The toxicity of 7 insecticides against the field resistance population of Plutella xylostella were determined, and the field efficacy test of 7 insecticides were conducted at the registered dosage. The results showed that: the LC50 value of spinosad, chlorantraniliprole, abamectin, chlorfenapyr, indoxacarb, diafenthiuron, beta-cypermethrin against P. xylostella was 1.14, 1.81, 2.27, 4.22, 4.59, 45.80, 156.96 mg/L, respectively; the resistance index of the P. xylostella against diafenthiuron, indoxacarb, spinosad was 2.14, 8.83, 9.50, respectively, and belonged to low resistance level; the resistance index against chlorfenapyr, chlorantraniliprole, beta-cypermethrin was 10.55, 30.17, 44.21, respectively, and the resistance level was medium level; the resistance index to abamectin was 113.50, belonged to high resistance level. In the field, spinosad, indoxacarb, chlorantraniliprole, diafenthiuron had better control efficacy against P. xylostella, after spraying for 7 days, the efficacy was 89.38%, 90.67%, 84.10%, 86.18%, respectively. The population of P. xylostella has different resistances to 7 insecticides, and there is a significant negative correlation between the field control efficacy and the resistance level of P. xylostella under the registration dosage.