Abstract: Manure and biological fertilizer was used in this article to study utilizing amount of these fertilizer and affect on yield and yield component. The result shows that using manure and biological fertilizer have obviously increased yield of rice than Nitrogen, Phosphors and Potassium mixed; Nitrogen, Phosphors mixed; Nitrogen and Potassium mixed and Nitrogen used only. The effects of manure and biological fertilizer on yield and yield components have confirmed. And high yield prescription of manure and biological fertilizer, phosphorus vivid reagent and nitrogen have selected and it can save nitrogen 12.5%~37.5% without using Phosphors and Potassium.