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中国农学通报 ›› 2012, Vol. 28 ›› Issue (12): 154-158.doi: 10.11924/j.issn.1000-6850.2012-0074

• 生物技术科学 • 上一篇    下一篇

SNP分子标记的研究及其应用进展

唐立群 肖层林 王伟平   

  • 收稿日期:2012-01-09 修回日期:2012-02-27 出版日期:2012-04-25 发布日期:2012-04-25
  • 基金资助:

    国家科技支撑计划;转基因生物新品种培育重大专项

Research and Application Progress of SNP Markers

  • Received:2012-01-09 Revised:2012-02-27 Online:2012-04-25 Published:2012-04-25

摘要:

SNP标记作为第三代分子标记,在分子遗传学、药物遗传学、法医学以及疾病的诊断和治疗等方面发挥着重要作用。介绍了SNP标记的定义与特点,对近年来以SNP标记为基础构建的Bin图谱、高通量SNP芯片分型以及以SNP标记为基础进行群体进化研究等三方面的应用概况进行了简述。提出了SNP标记现阶段发展存在的问题,并对其发展前景予以展望。

关键词: 草产量, 草产量

Abstract:

SNP (single nucleotide polymorphism) marker, as a molecular marker of the third generation, plays an important role in molecular genetics, pharmacogenetics, forensic medicine, diagnosis and treatment of diseases recently. In this paper, the definition and characteristics of SNP molecular marker were both introduced. And the application profiles of Bin map, high throughput SNP-chip classification and population evolution research on the basis of SNP molecular marker was presented respectively. Finally, the problems of SNP molecular marker at the present stage were proposed, and the prospects of SNP molecular marker was predicted as well.