G蛋白信号转导调节蛋白(RGS)研究进展

doi:10.11924/j.issn.1000-6850.2013-1149

摘要/Abstract

摘要： G蛋白信号转导导调节蛋白(RGS)是G蛋白信号转导通路中的负性调节因子，近年来，G蛋白信号转导途径一直是生物领域的研究热点之一。本研究总结了近年来RGS蛋白在动物和植物方面的研究进展，归纳了RGS蛋白的结构和分类；从RGS蛋白的GAPs作用、整合各种G蛋白信号系统、支架蛋白和调节细胞内运输等方面介绍了RGS蛋白的功能；阐述了RGS蛋白磷酸化、脂类修饰和RGS降解等调节机制，对RGS蛋白的深入研究有利于对信号通路的深入了解。

关键词: 产肉性能, 产肉性能

Abstract: Regulators of G protein signaling (RGS proteins) is a negative regulator in the G protein-mediated signaling. Recently, researches were focused on G proteins and RGS proteins. This review summarized investigative progress in animals and plant in recent years. The structure and categories were described detailed. The functions including acting as GAPs, integration G protein signaling, scaffolding protein and regulating cell transportation were analyzed. The regulatory mechanism of RGS protein was introduced from the aspect of phosphorylation, lipidmodification, degradation of RGS proteins and so on. Deep research of the RGS protein was conducive to know more about the signaling pathway.

朱小彬朱霞于一帆陈云. G蛋白信号转导调节蛋白(RGS)研究进展[J]. 中国农学通报, 2014, 30(6): 248-253.

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