Abstract: To understand the research progress of agricultural non-point source pollution (ANSP) in Chaohu Lake basin, and the research status and hot topics, CNKI, VIP and SCOPUS databases are chosen to get the published articles on ANSP in Chaohu Lake basin. The results showed that the focus of the ANSP researches in this region was controlling methods. Most of them provided qualitative approaches from source control, intermediate interception and the end treatment. Model and status of the ANSP in the region were also research highlights, foreign universal models were most used for verification and pollution load estimation. The major research institutions included Anhui Agricultural University and Hefei University of Technology. Ma Youhua team was the core one in this research field, and the major journals were Chinese Agricultural Science Bulletin, Anhui Agricultural Science Bulletin, Journal of Soil and Water Conservation, and Acta Scientiae Circumstantiae. Our findings show that: control direction is the study hotspot, and many literatures are on qualitative control method; quantitative study on control effect and ecological compensation standard are future research directions, and model innovation should be enhanced.