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中国农学通报 ›› 2011, Vol. 27 ›› Issue (33): 217-220.

所属专题: 生物技术

• 食品 营养 检测 安全 • 上一篇    下一篇

蛙皮活性抗菌肽最新研究进展

周庆峰 赵文锋 张向飞   

  • 收稿日期:2011-06-13 修回日期:2011-08-09 出版日期:2011-12-25 发布日期:2011-12-25
  • 基金资助:

    蛙皮抗菌肽 Brevinin-2GUb 促胰岛素释放作用及其分子机制研究

Progress in research of active antimicrobial peptides from the skins of frog

  • Received:2011-06-13 Revised:2011-08-09 Online:2011-12-25 Published:2011-12-25

摘要:

蛙皮抗菌肽是生物界中广泛存在的一类生物活性肽,是蛙类生物机体先天性免疫的重要防御成分。目前,从青蛙皮肤中获得了越来越多结构新颖、作用独特的活性抗菌肽,有望成为感染类以及糖尿病等疾病新的药物资源,该文通过对国内外相关文献进行检索,综合了国内外近年来的研究,对近年来蛙皮抗菌肽的活性研究概况进行综述。

关键词: 农产品 传播视角 品牌培育, 农产品 传播视角 品牌培育

Abstract:

Progress in research of active antimicrobial peptides from the skins of frog ZHOU Qing-feng1, ZHAO Wen-feng2,ZHANG Xiang-fei3 (1. Department of Life Science and Technology, ShangQiu Normal College, ShangQiu, 476000; 2. School of Life Science and Technology, China Pharmaceutical University, Nanjing, 210009) Abstract: Antimicrobial peptide from the skins of frog is a kind of bioactive peptide existed extensively in nature, and is one key component of the host-resistance apparatus so-called innate immunity. At present, a series of antimicrobial peptide with novel structures and unique function were isolated from frog resources, which are potential resources for anti-infective and diabetes therapeutic drug. By literature retrieval and induction, the progress in research of antimicrobial peptide from the skins of frog was reviewed in this paper. Key words: the skin of frog; antimicrobial peptide; insulin-releasing; activity