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中国农学通报 ›› 2012, Vol. 28 ›› Issue (8): 42-46.

所属专题: 生物技术 畜牧兽医

• 畜牧 动物医学 蚕 蜂 • 上一篇    下一篇

猪药物代谢酶的研究进展

李锐 贺亮 张文童 王强   

  • 收稿日期:2011-12-02 修回日期:2011-12-16 出版日期:2012-03-15 发布日期:2012-03-15
  • 基金资助:

    作物-饲料-畜禽食物链中毒死蜱残留行为及其风险评估研究

Progress of research on drug metabolic enzymes in pigs

  • Received:2011-12-02 Revised:2011-12-16 Online:2012-03-15 Published:2012-03-15

摘要:

药物代谢酶在猪体内外源及内药性物质的生物转化中起着至关重要的作用,细胞色素P450是猪肝脏中重要的代谢酶。此文对猪药物代谢酶的分类、细胞色素CYP亚型、CYP与药物相互作用的关系等重要研究领域的成果进行了详细阐述,并展望了猪药物代谢酶未来的研究方向,旨在为养猪业临床合理用药提供科学依据。

关键词: C值, C值

Abstract:

metabolic enzymes have the crucial role in metabolism of the exogenous and endogenous substances in pigs, Cytochrome P450 is the most important enzyme family. The progress on metabolic enzymes classification,pig cytochromes subtype,relationship between CYP and drug was reviewed. Pig metabolic future research focus was prospected. In this article we provided the scientific basis for reasonable utilization of clinical drug.

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