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中国农学通报 ›› 2012, Vol. 28 ›› Issue (23): 66-68.doi: 10.11924/j.issn.1000-6850.2012-0144

所属专题: 畜牧兽医

• 畜牧 动物医学 蚕 蜂 • 上一篇    下一篇

镉对鸡肝脏抗氧化系统功能以及中药四君子汤拮抗效应的影响研究

陈强 肖银霞 王立成 姜莉莉   

  • 收稿日期:2012-01-13 修回日期:2012-03-08 出版日期:2012-08-15 发布日期:2012-08-15
  • 基金资助:

    辽宁医学院青年科技启动基金项目

Research on Effect of Cadmium on Antioxidation System of Chicken Liver and Antagonistic Effect of the Traditional Chinese Medicine Sijunzi

  • Received:2012-01-13 Revised:2012-03-08 Online:2012-08-15 Published:2012-08-15

摘要:

为探讨中药四君子汤对镉中毒鸡肝脏GSH-Px、SOD活性抑制的拮抗作用。选用60只100日龄海兰公鸡,随机平均分为3组,对照组常规饲养,加镉组常规饲养的同时,添加CdCl2 150 mg/kg,中药四君子汤加镉组常规饲养的同时,添加CdCl2 150 mg/kg,添加1%中药四君子汤。分笼常规饲养,试验期为60天,这样就建立了亚慢性镉中毒及中药四君子汤拮抗模型。试验结果显示:肝脏谷胱甘肽过氧化物酶(GSH-Px)活性为对照组、中药四君子汤加镉组至加镉组依次降低;肝脏超氧化物歧化酶(SOD)活性为对照组、中药四君子汤加镉组至加镉组依次降低;肝脏丙二醛(MDA)含量为对照组、中药四君子汤加镉组至加镉组依次升高。表明日粮中添加中药四君子汤后可有效地提高机体的抗氧化能力。

关键词: 品种筛选, 品种筛选

Abstract:

In order to explore the traditional Chinese medicine Sijunzi’s antagonism to the activity of GSH-Px and SOD in cadmium poisoning chicken liver, 60 100-day-age Hayland roosters were selected to be divided into 3 random average groups. Control group1 was fed with the usual method. Control group 2 was fed with the usual method and added with cadmium the concentration of 150 mg/kg. Control group 3 was fed with the usual method, cadmium of 150 mg/kg and Sijunzi. All 3 groups were fed with normal diet in each cage. liver GSH-Px activity was set as control group. The group of Sijunzi with cadmium to the group of cadmium were declined in turn; liver SOD activity was set up as control group, the group of Si Junzi Tang with cadmium to the group of cadmium were declined in turn; set liver MDA content as control group, the group of Sijunzi with cadmium to the group of cadmium were increased in turn. The experiment indicated that daily diet added with traditional Chinese medicine Sijunzi could effectively improved the body’s oxidation resistance.

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