牛精原干细胞研究进展

摘要/Abstract

摘要： 精原干细胞(spermatogonial stem cells, SSCs)是雄性生殖系干细胞，位于睾丸曲细精管基膜上，既具有自我更新潜能，又具有定向分化潜能，是自然状态下出生后动物体内在整个生命过程中进行自我更新并能将基因传递至子代的惟一成体干细胞。根据国内外最新相关进展，系统评述了牛SSCs的生物学特性、分离纯化、冷冻保存、体外培养、永生细胞系的建立及移植等方面的现状及问题。

关键词: 大熊猫“丹丹”, 大熊猫“丹丹”, 肝胀, 脾胀, 子宫, 癌变皮, 光镜观察

Abstract: Spermatogonial stem cells (SSCs), the postnatal male germline stem cells, reside on the base membrane of the seminiferous tubules in testes. They are not only capable of self-renewing and differentiating but also the only adult stem cells in normal postnatal body that undergo self-renewal throughout life and transmit gene to offspring. According to the related reports most recently, the biological properties separation, purification, cryopreservation, in vitro culture, establishment of immortalized cell line and transplantation of bovine spermatogonial stem cells were discussed.

中图分类号:

Q813.1.1

吴建英,胡铁军,岳占碰,张学明,李子义,李德雪,. 牛精原干细胞研究进展[J]. 中国农学通报, 2007, 23(6): 28-28.

Wu Jianying, Hu Tiejun, Yue Zhanpeng, Zhang Xueming, Li Ziyi, Li Dexue,. The Progress of Bovine Spermatogonial Stem Cells Researches[J]. Chinese Agricultural Science Bulletin, 2007, 23(6): 28-28.

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