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中国农学通报 ›› 2011, Vol. 27 ›› Issue (9): 39-45.

• 农学 农业基础科学 • 上一篇    下一篇

黄单胞杆菌Ⅲ型效应子研究进展

车晋英 李岩强 王春连 赵开军   

  • 收稿日期:2011-01-30 修回日期:2011-02-22 出版日期:2011-04-25 发布日期:2011-04-25

Current Progress in the Research on the Type III Effectors of Xanthomonas

  • Received:2011-01-30 Revised:2011-02-22 Online:2011-04-25 Published:2011-04-25

摘要:

许多黄单胞杆菌通过Ⅲ型分泌系统将效应子注入到寄主细胞中,引起寄主的免疫反应或感病。最近的研究提供了大量的关于Ⅲ型效应子作为致病因子或激发子同寄主互作的实验数据。本文综述了黄单胞杆菌Ⅲ型效应子的分类及avrbs3、AvrRxv/YopJ、XopN、XopD家族的主要功能,重点介绍了Ⅲ型效应子的酶活性功能在同寄主互作过程中发挥的重要作用,如XopD的SUMO化作用;AvrBs3家族效应子在调节寄主基因转录方面的作用;XopN抑制PAMP介导的植物免疫反应的功能等。论文还对一些研究深入的Ⅲ型效应子及其与寄主的互作进行了比较详细的评述,讨论Ⅲ型效应子的研究对于植物抗病基因工程的影响及重要意义,并对Ⅲ型效应子的研究方向进行了展望。

关键词: 根芹菜, 根芹菜, 施肥, 产量, 硝酸盐

Abstract:

Many pathogenicities of Xanthomonas depend on a conserved type III secretion system which injects type III effectors into the plant cell, causing the host's immune response or susceptibility. Here, we present an overview about the classification of type III effectors from Xanthomonas and the main function of Avrbs3, AvrRxv /YopJ, XopN, XopD family. The effector proteins with enzymatic functions in the interaction of Xanthomonas with its host plants were highlighted, for example, the SUMO protease activity of XopD; Effectors of the AvrBs3 family can mimic plant transcriptional activators and manipulate the plant transcriptome; XopN suppresses PAMP-triggered immune responses during Xcv infection. Some of those expertly studied in depth and the interaction with their host factors were reviewed in detail. Finally, the impact of the type Ⅲ effectors’ research on plant disease resistance genetic engineering and the future prospects of research direction about the type III effectors were discussed.

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