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中国农学通报

中国农学通报 ›› 2012, Vol. 28 ›› Issue (8): 15-18.

所属专题： 畜牧兽医

• 畜牧 动物医学 蚕 蜂 • 上一篇    下一篇

银翘天甘中药制剂抗鸡体内大肠杆菌试验研究

蒋红 王宏军 周铁忠 刘丹   

  • 收稿日期:2011-10-10 修回日期:2011-10-24 出版日期:2012-03-15 发布日期:2012-03-15
  • 基金资助:

    辽宁省教育厅

Antimicrobial test to chicken E.coli on Chinese herbal preparation of Yinqiaotiangan

  • Received:2011-10-10 Revised:2011-10-24 Online:2012-03-15 Published:2012-03-15

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863

摘要：

为观察银翘天甘中药制剂抗鸡体内大肠杆菌的效果，将15日龄雏鸡用O2型大肠杆菌攻毒并开展预防和治疗实验。预防试验是用15日龄雏鸡O2型大肠杆菌攻毒同时口服银翘天甘中药制剂0.5 mL、1.0 mL、2.0 mL，1次/天，连用10天，测定发病率、死亡率和保护率；治疗试验是先用O2型大肠杆菌攻毒并建立疾病模型后口服上述药物，2次/天，连用10天，以头孢噻肟钠作为阳性对照，测定治愈率、有效率和死亡率。预防试验结果表明，银翘天甘中药制剂组实验动物死亡率均极显著低于感染对照组（P<0.01）；中、高剂量组对实验动物的保护率超过85%；在18日龄时，给药组实验动物发病率均极显著低于感染对照组（P<0.01）。治疗试验结果表明：银翘天甘中药制剂实验组感染雏鸡死亡率显著低于头孢噻肟钠阳性对照组（P<0.05）；中、高剂量组治愈率显著高于阳性对照组（P<0.05或P<0.01），高剂量组有效率显著高于阳性对照组（P<0.05）。由此表明，口服银翘天甘中药制剂能够有效预防和治疗鸡大肠杆菌病。

关键词: 产量性状, 产量性状

Abstract:

In order to investigate antimicrobial effect to chicken E.coli on Chinese herbal preparation of Yinqiaotiangan in vivo, The prevention and treatment test was carried with 15 days age chicken. In the prevention trial these chicken were attacked by the O2 type E.coli and taken orally 0.5mL,1.0mL and 2.0mL Chinese herbal preparation of Yinqiaotiangan respectively, at the same time. And then the incidence, mortality, and protective rate were detected when the Chinese herbal preparation were continuous used 10 d, once a day. In the treatment test these chicken were attacked by the O2 type E.coli and established the O2 type E.coli disease model, following taken orally 0.5mL,1.0mL and 2.0mL Chinese herbal preparation of Yinqiaotiangan respectively and injected cephalosporin latter sodium as positive control. The cure rate, effective rate and incidence were detected when the Chinese herbal preparation were continuous used 10 d, twice a day. The prevention trial results showed that the protective rate in experimental groups were higher than those in control (P<0.05),the incidence and mortality were lower than that of the control at 18th day (P<0.01),and the protective rate of middle and high dose group reached above 85%.The treatment test results showed that the incidence of the Chinese herbal preparation groups was lower than that of cephalosporin latter sodium group(P<0.05), the cure rate of middle and high dose group were higher than that of cephalosporin latter sodium group(P<0.05 or P<0.01) , and the effective rate of high dose group was higher than that of cephalosporin latter sodium group(P<0.01).So chicken E.coli disease could be effectively prevented and treated by oral the preparation of Yinqiaotiangan.