生物质谱技术研究进展及其在蛋白质组学中的应用

doi:10.11924/j.issn.1000-6850.2014-0018

摘要/Abstract

摘要： 随着蛋白质组学的快速发展，生物质谱技术在蛋白质组学中的应用不断深入，逐渐成为这一领域的核心技术。为系统揭示生物质谱技术在蛋白质组学中的具体应用。本文综述了生物质谱仪器的快速发展和其在蛋白质鉴定、翻译后修饰和蛋白质定量分析等方面的应用和研究进展。生物质谱技术的进步加快了蛋白质组学研究的进程，但样品的复杂性和庞大数据的处理是生物质谱技术面临的不可避免的挑战。相信随着生物质谱技术的不断完善和改进，必将会在蛋白质组学研究中发挥更加重要的作用。

关键词: 模糊综合评价, 模糊综合评价

Abstract: With the rapid development of proteomics, biological mass spectrometry technology had provided the profound application in proteomics, it was gradually becoming the core technology in this field. In order to reveal the specific application of biological mass spectrometry technology systemly in proteomics. In this paper, we reviewed the development of biological mass spectrometers and the applications of biological mass spectrometry technology in protein identification, posttranslational modifications and quantitation of proteins. Biological mass spectrometry technology promoted the process of the proteomics, but the complexity of the sample and the tremendous of data analysis was inevitable challenge for the technology. We believe that with the consummation and evolution of biological mass spectrometry technology, it would play a greater role in the proteomics.

杨倩,王丹,常丽丽,孙勇,靳翔,王旭初. 生物质谱技术研究进展及其在蛋白质组学中的应用[J]. 中国农学通报, 2015, 31(1): 239-246.

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