中国农学通报 ›› 2019, Vol. 35 ›› Issue (30): 84-90.doi: 10.11924/j.issn.1000-6850.casb18050042
贾文斌, 辛富刚, 孙玉霞, 姚川, 丁汉凤
收稿日期:
2018-05-10
修回日期:
2018-10-25
接受日期:
2018-11-07
出版日期:
2019-10-25
发布日期:
2019-10-25
通讯作者:
丁汉凤
Received:
2018-05-10
Revised:
2018-10-25
Accepted:
2018-11-07
Online:
2019-10-25
Published:
2019-10-25
摘要: 二十二碳六烯酸(docosahexaenoicacid,DHA)是具有重要生理功能而人体自身无法合成的一类多不饱和脂肪酸,而隐甲藻(Crypthecodinium cohnii)是生产二十二碳六烯酸的理想原料之一。本文为了将来开展隐甲藻规模化生产DHA研究,综合分析了隐甲藻种质、DHA生物合成途径、培养条件对DHA积累的影响等方面的问题。具体为(1)组成隐甲藻的同胞体DHA产量不同,可利用诱变的方式筛选突变体获得新的优良品系;(2)隐甲藻DHA的生物合成与其他脂肪酸的生物合成不同,对其合成途径进行了推测,可能为PKS途径;(3)环境条件,包括温度、光照、pH值、溶氧量、接种量、消泡处理等,以及培养基组成,包括碳源、氮源、无机盐及微量元素等培养条件均会影响藻体中DHA的含量。诱变是获得高产DHA藻株的可行性方法,以此提出了对隐甲藻生产DHA的研究展望。
贾文斌,辛富刚,孙玉霞,姚川,丁汉凤. 隐甲藻生产二十二碳六烯酸的研究进展[J]. 中国农学通报, 2019, 35(30): 84-90.
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