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中国农学通报

中国农学通报 ›› 2011, Vol. 27 ›› Issue (29): 102-106.

所属专题： 畜牧兽医

• 食品 营养 检测 安全 • 上一篇    下一篇

金花葵黄酮对糖尿病模型小鼠脂代谢的影响

王晓玉 魏文 何计国   

  • 收稿日期:2011-04-18 修回日期:2011-05-06 出版日期:2011-11-15 发布日期:2011-11-15

Effect of Abelmoschus Manihot Flavone on Lipid Metabolism in Diabetic Mice

  • Received:2011-04-18 Revised:2011-05-06 Online:2011-11-15 Published:2011-11-15

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摘要：

观察金花葵总黄酮对糖尿病模型小鼠脂代谢以及SOD的影响，将链脲佐菌素(STZ)诱导成功的糖尿病小鼠模型随机分为正常对照组、金花葵黄酮高剂量组，中剂量组和低剂量组，阴性对照组和阳性对照组。灌胃4周后检测血脂和超氧化物岐化酶(SOD)的变化。结果表明，与阴性对照组相比，金花葵黄酮干预小鼠总胆固醇下降（P<0.01），高密度脂蛋白胆固醇上升（P<0.05），SOD上升（P<0.01）。适量金花葵黄酮对糖尿病小鼠脂代谢紊乱有明显的改善作用，并有显著的体内抗氧化能力。

关键词: 灰树花, 灰树花, 白灰树花, 蛋白质, 氨基酸, 营养评价

Abstract:

To explore effect of Abelmoschus manihot flavone (AMF) on blood lipids and SOD on diabetic mice. The diabetic mice model was made, the mice were divided randomly into 5 groups according to the blood glucose: normal control group, blood glucose positive control group, flavone high-dose, middle-dose, low-dose group. The level of blood lipid and SOD index were observed. Results showed that: in diabetic group, the blood lipid was significantly increased in comparison with control group. One dose of AMF could significantly increase SOD and HDL-c, at the same time, the TC was significantly decreased. AMF could effectively correct the discord of lipid metabolism and improve antioxidation ability invivo in diabetic.

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