Abstract: Anqing wetland along the Yangtze River, which has intricate topography, numerous lakes and a large quantity of tributaries, is situated in the lower reaches of the Yangtze River. The DaBie mountain and Yangtze River lie on its north and south respectively. According to the related literature of history, basic geography data, and the remote sensing map-making research, this paper analyses the distribution of the lakes and rivers in the natural protection area, and the variation of the waters, in order to provide scientific reference to the related research on the utilization and protection of wetland ecosystems, the soil erosion of mountainous district and the variation of the land resources.