Abstract:

The mothproofing tablets composed of dry eupatorium powder, lavender oil and camphor were prepared. The effects of various factors on the release rates of active agents from the mothproofing tablets were investigated. The optimized formulation was obtained by efficacy test. The camphor and lavender oil-containing mothproofing tablets were prepared by the method of direct compression using eupatorium dry powders as a matrix material. The factors influencing the release rates of active agents from the tablets were investigated using in vitro dynamic release experiment. The efficacies of pure camphor tablets, pure dry eupatorium-powder tablets and the other tablets with different formulations were evaluated using the black carpet beetles as test insects. The dry eupatorium powders had good compressibility. The tablets had good sustained release effects for lavender oil, which were prepared under the compression force of 10 MPa using silica particles as the adsorbent for lavender oil. The fabric damage degree was evaluated as grade 3 and 4 respectively for pure camphor tablets and pure eupatorium-powder tablets, both of which did not meet the registration standard (grade≤2). The formulations were optimized to obtain the best efficacy when the mass fraction of camphor was 60% (m/m) and the mass fraction of lavender oil was 6% (m/m) and the remaining fraction was dry eupatorium powder. The fabric damage degree of this optimized formulation was grade 1, meeting even excelling the registration standard.