Abstract: The paper aims to explore the cadmium-tolerance of Chamaecrista rotundifolia. The authors studied the effects of Cd stress on the growth and development, mineral nutrient uptake, Cd accumulation and distribution of C. rotundufolia seedlings of different varieties (CIP86134 and ATF3248) by using nutrient solution culture experiment. The results showed that: Cd stress inhibited the growth of C. rotundufolia seedling, and the plant height and leaf emergence rate were lower than that of CK, and decreased the biomass accumulation of C. rotundifolia and the absorption of Ca, Mg, Cu and Zn; CIP86134 and ATF3248 were not Cd-tolerant plants, and their tolerance of the Cd concentration was 33.4 mg/kg and 33.1 mg/kg, respectively. By comparing morphological diagnosis, biomass and the amount of Cd absorption, the tolerance ability of CIP86134 to Cd stress was stronger than that of ATF3248. CIP86134 is more suitable for the ecological restoration of Cd polluted soil.