Abstract: Being Orchidaceae plants, Cymbidium hybrid possessed high worth for viewing and commerce. This article summarized the research progress on cross breeding, mutation breeding and genetic engineering of Cymbidium hybridum. The studies on the karyotype analysis applications, the choice of hybrid parents, molecular marker-assisted selection and genetic engineering were reviewed. Finally, the author put forward that using tissue culture as the main means to carry out a variety of ways in orchids breeding had broad prospects.