Abstract: To improve soil improvement, tobacco quality and make sustainable development of flue-cured tobacco production in Huidong tobacco growing-area were the purpose of this research. With tobacco-green manure crop rotation field experiments and indoor analysis for five consecutive years from 2008 to 2012, the field experiment was conducted to study long-term green manure to field on the yield, quality of flue-cured tobacco and soil improvement. The results showed that green manure could improve average price, fine tobacco ratio and economic benefits. The potassium content was significantly increased and the chemical composition was more coordinate. The appearance quality was better, and smoking score was higher while the used amount was 15000-22500 kg/hm². Meanwhile, the soil enzyme activity, soil nutrient and water content were also enhanced. It played an important role in soil improvement and recovering the soil fertility.