Abstract: [Abstract] The objective of this experiment was to examinate the efficacy of hydrogen peroxide dilute solutions in removing the 3,4-benzopyrene in rehmanniae by means of immersion method. Single factor and orthogonal experiments were done to examinate the efficacy of hydrogen peroxide dilute solutions of different temperature, different immersion time and different concentration in removing the 3,4-benzopyrene in rehmanniae and to find out the optimum technology parameter. The result showed that, (1) 90% 3,4-benzopyrene in rehmanniae can be removed by hydrogen peroxide dilute solutions of concentration range used in this experiment; (2) immersion time was the most important factor in the process of removal of the 3,4-benzopyrene in rehmanniae, while temperature was the second important factor and concentration of hydrogen peroxide dilute solution is the last; (3) the technological condition combination to remove the 3,4-benzopyrene in rehmanniae was optimum when the concentration of hydrogen peroxide dilute solution was 2%, the temperature of solution was 37℃ and immersion time was 50 minutes. The conclusion was that by means of immersion method, hydrogen peroxide dilute solution can be used by interrelated industrial enterprises to remove the 3,4-benzopyrene in rehmanniae.