Abstract: Blast is one of the major diseases, which affect rice production. There seems no specially effective way to control the disease in production, but more often, it depends on the resistibility in the rice itself to limit the epidemic of blast. Therefore, it is significant to conduct the studies on inheritance and breeding of blast resistance in rice. At present there are more than 40 blast resistant genes, which are tested and positioned, and 2 blast resistant genes i.e. Pi-b and Pi-ta, which are cloned. The following strategies can be adopted in breeding for blast resistant rice varieties: extensively collect blast resistant germplasm; the highly resistant materials which have been selected naturally in the seriously blast-diseased areas and the resistant materials with resistant genes positioned can be used as key parental lines; observe the change in the structure of blast pathogenic populations so as to gain exact information related to the change of races; transfer some resistant genes through the combination of conventional sexual hybridization with trans-gene technology; combine the artificial inoculation, molecular marker and on-diseased-nursery test together for elevating the accuracy in the testing of the resistibility in the progenies of a hybrid as well as for accelerating the breeding progress.