Abstract: To investigate the safety of trace elements in soils, the greenhouse pot method was be used to study the soil effective content of zinc and boron on tobacco growing and other elements accumulation. The results showed that when the soil available zinc content reach 4.69 mg / kg or effective boron content reach 3.32 mg / kg, the tobacco plants might exhibit symptoms of poisoning; when soil zinc content is high, more zinc alloted to the leaves, and when the soil boron content is high, more boron distributed to the stem; boron could promote the accumulation of ferrum and magnesium, and inhibit the accumulation of calcium, zinc could promote the accumulation of copper, and inhibit the accumulation of ferrum.