Abstract: In order to provide basis for the production of Medicago sativa L. in saline-alkali soil, the author assessed the effect of exogenous water-soluble vitamins (VB₁, VB₂, VPP, VB₆, VH, VB₁₂ and VC) on the seed germination and recovery of M. sativa under 14610 mg/L NaCl stress. The results showed that 62.5 mg/L VPP significantly increased the shoot fresh weight after the recovery germination. 1000 mg/L VB₆, 500 mg/L VB₁₂ and 1000 mg/L VC substantially promoted the germination under high salinity stress, but had no significant impact on the recovery germination after the stress was relieved. 250 mg/L VB₁₂ significantly improved both the germination under high NaCl stress and the recovery germination, reduced the mortality rate under high NaCl stress from 19.667% to 4.667%. VB₁, VB₂ and VH failed to effectively alleviate the inhibitory effect of high NaCl stress on seed germination. The experiment showed that exogenous VB₆, VB₁₂ and VC could play a role in regulating the seed germination characteristic of M. sativa under high NaCl stress.