Abstract: The study aims to select suitable varieties with drought resistance, water saving and high efficiency in the region, and explore an irrigation model matching these varieties, which can improve the water use efficiency. The essay can provide theory basis for dry farming water-saving culture and drought resistance breeding of wheat cultivars. ‘Luo han 8 hao’, ‘Xin mai 26’ ,‘Ai kang 58’ and ‘Zhou mai 18’ were used as test materials. Two different irrigation models were set up, including no irrigation (W0) and watering twice (W1). The effects of different irrigation models on dry matter accumulation, distribution, transport, yield and yield components of four wheat varieties were studied with split plot design. The results showed that, there was no significant difference about dry matter accumulation and ratio of grain among 4 varieties, whereas the amount of traffic, transfer rate and contribution to grain performance of dry matter was not consistent in different organs. The difference of spike dry matter between ‘Luo han 8 hao’ and ‘Zhou mai 18’ was significant. Under the irrigation model W0, because of the water restriction, the yields of all four varieties declined, ‘Luo han 8 hao’ had the smallest fall range, whereas ‘Zhou mai 18’ had the biggest fall range. In summary, the water sensitivity of ‘Luo Han 8 Hao’ was poor, and its ability of drought resistance was superior to that of the other three varieties.