Abstract: Effects of irrigation and nitrogen application on the yield and quality of high-yield wheat were explored, in order to provide a scientific basis for breeding new varieties in the future.‘Lin Y7287’bred by Wheat Research Institute of Shanxi Academy of Agricultural Sciences was used as the material. The split plot design was used in this study, 3 irrigation periods as the main plot, 3 nitrogen application periods as the subplot. The grain yield, protein content and part of dough rheology characteristics were analyzed. The results showed that, irrigation and nitrogen interaction had significant effects on the quality and yield of‘Lin Y7287’. Under W3N3 treatment, the grain yield of‘Lin Y7287’was the highest, 10124.48 kg/hm2. The protein content, wet gluten content, dry gluten content, and stability time was 14.86%, 34.1%, 10.2%, and 368 s, respectively. Moreover, the proportion of protein components was coordinated. Therefore, W3N3 treatment was the ideal interaction method.