Abstract: Chenopodium ambrosioides, Chenopodiaceae, an annual or perennial erect herbaceous plant, was firstly discovered in northern Taiwan in 1864 and listed in he Directory of the Second Batch of Alien Invasive Plant Species on January 7, 2010. At present, studies on C. ambrosioides are focusing on its biology, ecology, chemical constituents, allelopathy and resistance, and its invasive mechanism is presumed as chemical weapon, such as vigorous secondary metabolism, strong allelopathic potential and better stress resistance. No research has been conducted from the perspective of molecular biology, like genetic evolution characteristics, molecular marker on the invasion and metabolomics. Particularly, the comparison of seed germination and growth rate of C. ambrosioides and indigenous plant was absent. Therefore, more attentions should be paid to study molecular basis and priority effects of C. ambrosioides in the future.