Abstract: The paper aims to effectively prevent and migigate the impact of frost disaster on agricultural production in high-cold region of Qinghai province,and provide a reliable basis for reasonable development of agricultural climate regionalization. Based on the daily average air temperature data and the daily minimum temperature of Guinan county meteorological staion from 1961 to 2017,by using linear tendency estimation and M-K mutation analysis,several elements were analyzed,including the first frost date,the last frost date,the frost-period,and accumulated temperature of the frost-free period.The results showed that the First frost date assumes a significantly delayed trend,and last frost date assumes a significantly early trend. The Frost-free period assumes a significantly long trend,and the advanced magnitude of last frost date is treater than the delayed magnitude of first frost date.The frost-period was an insignificant tendency to delay; the accumulated temperature of the frost-free period was a significantly added trend.The first frost date had a advanced climate abrupt in 1972,the last frost date and the frost-period had a delay climate abrupt in 1970,the accumulated temperature of the frost-free period had a increased climate abrupt in 1977.