Abstract: Using the acid rain data, meteorological data, soil type data and DEM data of Xuyi County, we selected summer high temperature days, acid rain, soil type, altitude as key factors influencing lobster growth and built the agro-climatic zoning model with analytic hierarchy process method. We adopted ArcGIS 10.0 to divide the climatic suitability zoning of lobster cultivation in Xuyi. The results show that the suitable areas mainly distribute in north Xuyi, and the relatively suitable areas mainly locate in hilly areas in the southeast, and the unsuitable areas locate in the low hilly area in the southwest. The study could provide references for planning layout of lobster farming in Xuyi County.