The micro powdered seed coating chemical formula for preventing maize head smut was chosen out through indoor and pot experiment. And determined technological process of diniconazole seed coating chemical. The prevention from maize head smut and effect on corn growth by dose of diniconazole seed coating chemical and treatment was confirmed through pot experiment, field test and regional test. The results showed that germination percentage and germinating energy had increasing trend by 5% diniconazole micro powdered seed coating chemical. The prevention from maize head smut was 47.0%~60.3%, the increasing yield was 38.6%~58.7% under the vaccinate condition using diniconazole micro powdered seed coating chemical for wrapping. The prevention from maize head smut was71.7.7%~96.2%, the increasing yield was 6.8%~15.6% which were demonstrated by other place experiment. The dose ratio of drug and seed was 1:200~300 which was recommended on process.