Abstract: The effects of bio-organic fertilizer on the yield of cassava were studied in this experiment, of which the cassava variety FUXUAN01 and the bio-organic fertilizer produced by LIDA company were used as materials. The result showed that not only can the bio-organic fertilizer promote the stems and leaves of cassava growth, increase the chlorophyll content and the photosynthesis of leaves, and improve the physiological metabolism of cassava but also strengthen physiological function of anti-senility, promote the photosynthetic organism to transfer to the tuber root and increase the yield and starch content in the tuber root of cassava.