Abstract: Flaxseed is rich in α-linolenic acid, lignans and other nutritional components, but the presence of cyanogenic glucosides restricts its application in feedstuff and foodstuff. A study was conducted to determine the effectiveness of reducing the hydrogen cyanide (HCN) content of flaxseed by three processing methods. Flaxseed was processed by solvent extracting, microwave roasting and water boiling. The effectiveness in reducing HCN in flaxseed by these processes was monitored through HCN measurements by titration method. The results indicted the following.The HCN content was 157.68mg/kg in raw flaxseed. Microwave roasting of flaxseed reduced the HCN content by 95.57%; solvent extracting once reduced HCN content by 52%, twice by 80%, and thrice by 89%, and the water boiling reduced by 88.12％。Among these the microwave roasting method is the most effective method in removal of HCN; the solvent extracting method is easier to realize an industrialized production, the autoclaving and water boiling methods can be used only under special circumstance.