Abstract: In order to select quality flue-cured tobacco varieties, which were appropriate for planting at Liuyang, the field comparison test of 7 varieties were conducted and their agronomic, botanic, economic characteristics, disease resistance, outward appearance quality and inherent quality were studied at Liuyang, Hunan province. The results showed that: (1) the plant height of 97-6-4 and 97-7-11 were higher than CK(K326), the node length of 97-6-4 were biggest in all varieties, the average leaf number of 6 varieties were less than that of CK(K326), the single leaf weight of 6 varieties were higher than CK(K326) besides HY-9-7 and HT06, the growing stage of all varieties had no significant different, which were middle maturing variety, between 116 d and 121 d. (2) The disease index against TMV of 6 varieties were lower than CK(K326), the disease index against the Granville wilt of 97-6-4 were lowest in 7 varieties, the disease index against Black shank disease of HT06 were lowest in 7 varieties, the disease index against Climate spot of CK(K326) were higher than that of 6 varieties. (3) The maximum yield and value were observed at variety CY9506. HT06 had the highest proportions of top and middle class tobacco leaves. (4) CY9506 and 97-7-11 possessed the best outward appearance quality and inherent quality. Based on the yields and qualities, CY9506 and 97-7-11 should be recommended for further demonstration at Liuyang.