Abstract: Abstrect:The effects of LPS of Aeromonas hydrophila on anti-oxidation function immune function digestion funtion of ophiocephalusargus were improved under the LPS of Aeromonas hydrophila; The different density embroiders of LPS to Ophiocephalusargus’s oxidation resistance performance ,the immunologic function and the digestion function enhancement effect existence difference ，The anti-oxidation function of ophiocephalusargus were improved under the treament of 0.8mg/ml LPS of Aeromonas hydrophila .After the 10st day the time in the blood of Ophiocephalusargus, the activities of the CAT enzyme in the blood of Ophiocephalusargus was 0.17U and SOD was 16.56U ,they were higher than the treament of CK. The activities of bacteriolysin vigor in the blood 、 the amylase and the proteinase vigor in the gastro-interstinal tract were improved under 0.6mg/ mL LPS treament , After the 20st day, the activities of bacteriolysin vigor in the blood of ophiocephalusargus was the highest,it was up to 0.399U,After the 10st day, the activities of the amylase was 17.21U and the activities of the proteinase vigor was 0.36U,they were higher than the treament of CK.