Abstract: In order to provide a base for soil testing and fertilizer-applying prescription in Danzhou city of Hainan province, the ability of paddy soil nutrient supply and the fertilizer efficiency of NPK had been studied by the methods of “3414” field experiment in Danzhou city of Hainan province. The quadratic equation in three variables fertilizer response model had been established. The result showed that Urea（nitrogenous fertilizer）use-efficiency was 40.1%, calcium superphosphate (Phosphorous fertilizer) use-efficiency was 15.2%, potassium chloride (potassium fertilizer)use-efficiency was 37.1%. According to the quadratic equation in three variables fertilizer response model, the economic optimum application rate of nitrogenous fertilizer, Phosphorous fertilizer and Phosphorous fertilizer were N 159.6 kg/ha, P2O5 40.8 kg/ha and K2O 55.2 kg/ha, respectively.