Abstract: Abstract: This article in view of the tobacco climate scab question which often occurs in Yuxi tobacco production. According to the internal factor (Nutrition of Tobacco), take the rhizosphere soil and the leaves of all part position of plant as the exploration object, the distribution of disease in the field and the change of leaf nutrient has been researched by the method which combined field investigation, gathering pair samples and detection and analyse indoor. The result showed that climate scab mostly (83.5%) occurred on between 4th to 7th leaf (From down to up) during the earliest of anthesis. The internal factor is that it contented overmuch Nitrogen, Calcium and Magnesium but lack Potassium in the plants of tobacco which climate scab occurred on. Thus the rates of N/K, Mg/K and Ca/K were increased that result in unbalancing of between Nitrogen, Calcium, Magnesium and Potassium. Also, the basic reason what with overtop content effective Nitrogen (especially NO3－N and NH4－N ) and interchanging Magnesium and Potassium and lower content effective Potassium in the soil. Key word: flue-cured tobacco; climate scab; nutrition of soil; nutrition of tobacco