Abstract: Abstract: 【OBJECTIVE】A full set of disease resistance candidate genes encoding NBS-LRR in a complete genome of Arabidopsis thaliana were analyzed. 【METHOD】 Structural diversities, physical positions, and phylogenetic relationship were studied by TAIR and Pfam web, database, Chromosome Map Tool, MEGA 3.0 and ClustalX software. 【RESULTS】 204 genes containing NBS domain were found in genome and most of those were located in 1 and 5 chromosome. The NBS-LRR family genes on different chromosomes exist in the form of monogenic gene or gene clusters, and 71.6% of the NBS-LRR genes were located in gene clusters. That showed there are much copy phenomenons in the evolution of disease resistance genes of Arabidopsis thaliana.