Abstract: 【OBJECTIVE】Aiming at the unreasonable application of nitrogen, phosphorus and potassium fertilizer on the production of hybrid rice in the Jianghuai region;【METHOD】the relationship between the yields and the basic soil fertility, farmer accustomed fertilization and expert recommended fertilization in the Jianghuai region was studied by means of field experiment at five different plots to provide a theoretical basis for improving farmers’ fertilization effect and establishing high-yield and good-quality cultivation techniques in the Jianghuai region, Anhui province.【RESULTS】The results showed that, there were significant regional differences on basic fertility, increasing in yield and contribution rate of fertilizer in the paddy field of Jianghuai region.Fertilizing structure of farmers in rice production in the Jianghuai region had some problems, such as fertilization deficiency, unsuitable fertilizing proportion and great difference in different region.Expert recommended fertilization had significant effect on decreasing nitrogen application amount, adopting suitable nitrogen operation method and increasing phosphorus and potassium application amount, as well as balancing nutrient, meeting the demand of high yield of rice and enhancing fertilizer efficiency and use efficiency for the purpose of high production and high efficiency.【CONCLUSION】Based on our field results, it revealed that in the Jianghuai region of Anhui province, recommended fertilizer amounts were 150~180 kg.hm-2 for N, 60~90 kg.hm-2 for P2O5, 75~105 kg.hm-2 for K2O at the rice yield level of 9000~9750 kg.hm-2. 40~50% of the total amount is basal fertilizer, and 20~30% and 20~30% for tillering fertilizer and ear fertilizer, respectively. All phosphorus was used as basal fertilizer, and 60% of potassium fertilizer as base fertilizer, 40% for jointing fertilizer.