Abstract: Abstract [Objective] To set up the method of detecting the essential oils from Pogostemon cablin and establish the quantitative determination on Pogostemon cablin content. [Method] The essential oil was analyzed quantitatively and qualitatively on GC-MS instrument. For controlling the quality, GC fingerprint of Pogostemon cablin was set up by using GC-MS. [Result] Nine compounds including patchouli alcohol and pogostone were identified among 19 main peaks in three samples sold in the market.[Conclusion] The fingerprint can help distinguish the quality and assess the differences of Pogostemon cablin in various areas in China.