Abstract: This paper studies the effects of Ganoderma lucidum spore germination factors of Ganoderma lucidum extract medicinal ingredients and spores lay the foundation for breeding. The use of slide culture method compression rate of spore germination. Focused on Ganoderma lucidum at different temperatures, pH, oxygen and metal ions under the germination conditions for the existence of the situation. The results showed that Ganoderma lucidum spores in 28 ℃, pH5, oxygen, dark conditions, the germination rate of up to 48h culture 70%; 0.1mg/ml concentration of MgSO4, CaCl2, FeC13 promote spore germination.。