Abstract:

This study investigated the antifungal activity of alkaloids from Macleaya microcarpa in vitro and in vivo so as to reveal its antifungal activity. The bioassay results indicated that the alkaloids inhibited mycelial growth of 11 species investigated plant-pathogenic fungal in vitro. It especially could markedly inhibited the mycelial growth to Botrytis cinerea and Rhizoctomia solani. Their EC50 value against B. cinerea and R. solani were 0.022 g?L-1 and 0.024 g?L-1, respectively. The spore germination EC50 value against B. cinerea, Alternaria alternate and Exserohilum turcicum were 0.028, 0.032 and 0.064 g?L-1, respectively. In addition, protective effect and therapeutic effect of thymol (0.75 g?L-1) against the B. cinerea. were 72.01% and 60.28% in potted, respectively, which is no significant difference between Procymidone and thymol.