Abstract:

This study was aimed to investigate the effect of different dosages of melamine and cyanuric acid on the renal and orchic function of dogs. In these experiments, total 30 healthy male beagles (8-months old) were randomly divided into 5 groups, and they were fed with different dosages of capsules which had already been mixed by melamine and tricyanic acid. During the first 29 days of these tests, the mortalities of 5 groups, the composition and their ratioes of urinary sediment and the proportionalities of UPRO/UCRE were obtained. The results showed as following: ①the mortality of Group 4 was the highest one among all the groups (66.7 %); ②urinary sediment were composed by ammoniomagnesium phosphate crystal, yellow crystal, acicular crystal, epithelium of renal tubule, squamous cell, and transitional epithelium;the urinary sediment relevance ratio grows along with the dosage increase and the period extending; ③the proportionalities of UPRO/UCRE of each group were nearly normal on the whole;④Arrest of pathological changes, such as the form of crystallization, the nature nephritis and the fatty cell denatured occoured in higher dose of melamine and cyanuric acid in kidney but not in testis. Conclusion: it might be concluded that the high dosage of melamine and cyanuric acid be harmful to the renal normal function of male Beagles, but not influence it in their testis.