Abstract: Compared with chemical fertilizer, the influence of high efficiency organic fertilizer on Chinese angelica root’s configuration, weight, yield and Ditylenchus destructor occurring rate was studied by field test. Conclusions were drawn as follows: By using high efficiency organic fertilizer, fresh and dry root- head diameter were 3.67cm and 2.57cm, which increased 10.54% and 7.08% than using chemical fertilizer; fresh and dry main root diameter enhanced 7.69% and 6.60% respectively; dry root weight was 38.82, which improved 15.02% than using chemical fertilizer, and D/F increased 40%; dry angelica root yield increased too, reached 2371.84 ㎏/hm2; using high efficiency organic fertilizer reduced Ditylenchus destructor occurring rate ,which was 6.95%,lower than using chemical fertilizer about 17.04%.So high efficiency organic fertilizer is helpful to get high yield and good quality on Chinese angelica.