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中国农学通报 ›› 2015, Vol. 31 ›› Issue (35): 23-26.doi: 10.11924/j.issn.1000-6850.casb15050116

所属专题: 畜牧兽医

• 畜牧 动物医学 蚕 蜂 • 上一篇    下一篇

规模化养殖场猪粪源沙门氏菌的耐药性调查

江萍,夏利宁,苏战强,林亚军   

  1. 新疆农业大学动物医学学院,新疆农业大学动物医学学院,新疆农业大学动物医学学院,新疆农业大学动物医学学院
  • 收稿日期:2015-05-21 修回日期:2015-08-08 接受日期:2015-08-25 出版日期:2015-12-18 发布日期:2015-12-18
  • 通讯作者: 夏利宁
  • 基金资助:
    国家自然科学基金项目“新疆猪源大肠杆菌耐药基因的流行性调查及其传播机制研究”(31260614)。

Resistance of Salmonella Isolates from Swine Fecal in a Pig Farm to Antibiotics

江萍,, and   

  • Received:2015-05-21 Revised:2015-08-08 Accepted:2015-08-25 Online:2015-12-18 Published:2015-12-18

摘要: 为了解新疆乌鲁木齐周边某规模化猪场猪粪源沙门氏菌对临床常用抗菌药物的耐药情况,并将耐药数据用于指导该养殖场临床合理用药,采用琼脂稀释法对550 份粪样中分离出的58 株沙门氏菌进行最小抑菌浓度测定。结果显示:沙门氏菌对四环素(100.0%)、环丙沙星(96.6%)、恩诺沙星(94.8%)、阿莫西林/克拉维酸(91.4%)、卡那霉素(89.6%)、氟苯尼考(84.5%)和氨苄西林(75.9%)7 种药物呈现高水平耐药;对阿米卡星(58.6%)、安普霉素(55.2%)、诺氟沙星(51.7%)和庆大霉素(50.0%)呈现中等水平耐药;仅对头孢噻呋(8.6%)敏感。该养殖场猪粪源沙门氏菌对临床常用抗菌药物耐药情况严重,临床应考虑联合用药、轮换用药。

关键词: 免耕, 免耕, 旋耕, 亚麻, 原茎, 种子, 产量

Abstract: In order to investigate the resistance of Salmonella isolated from a pig farm and guide reasonable use of clinical antimicrobial drugs in Urumqi, Xinjiang, minimum inhibitory concentrations of 58 strains of Salmonella isolated from 550 fecal samples were determined by agar dilution method. The results showed that the resistance rate of Salmonella presented a high level to tetracycline (100.0% ), ciprofloxacin (96.6% ), enrofloxacin (94.8%), amoxicillin/clavulanate (91.4%), kanamycin (89.6%), florfenicol (84.5%) and ampicillin (75.9%); and presented a moderate level to amikacin (58.6%), apramycin (55.2%), norfloxacin (51.7%) and gentamicin (50.0%); and was sensitive to ceftiofur (8.6%). The resistance rate of Salmonella from pig fecal in this farm to commonly used antibiotics was serious, indicating that alternative and combined use of antibiotics should be adopted in the clinic.

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