Abstract: Construction of the important carrier, technology innovation platform in professional town, has important practical significance. It helps to solve common industrial technical problems in professional town. It helps to improve the ability of independent innovation for SMEs. It helps to promote the industrial structure optimizated and upgraded and industrial agglomeration, then ultimately achieve the sustainable economic development in professional town. This paper first analyzes the concept of technology innovation platform in professional town, platform structure and the internal relations. Then analysis the construction mechanism of technology innovation platform in professional town thoroughly. And propose construction of mechanisms such as the non-zero cooperative game; complementary strengths to create synergies; resource sharing, risk-sharing; cooperation innovation, saving transaction costs construction of mechanism. It provides a theoretical basis for construction of technology innovation platform in professional town, also for the design of operating mechanism and safeguards arrangements.